139260-81-4

Basic information

• Product Name: N-[9-[(2R,4R,5R)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-hydroxytetrahydrofuran-2-yl]purin-6-yl]benzamide
• Synonyms: N-[9-[(2R,4R,5R)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-hydroxytetrahydrofuran-2-yl]purin-6-yl]benzamide
• CAS NO: 139260-81-4
• Molecular Weight: 657.726
• Mol File: 139260-81-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-[9-[(2R,4R,5R)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-hydroxytetrahydrofuran-2-yl]purin-6-yl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[9-[(2R,4R,5R)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-hydroxytetrahydrofuran-2-yl]purin-6-yl]benzamide(139260-81-4)
• EPA Substance Registry System: N-[9-[(2R,4R,5R)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-hydroxytetrahydrofuran-2-yl]purin-6-yl]benzamide(139260-81-4)

Safety Data

• Hazardous Substances Data: 139260-81-4(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 125944-20-9 N⁶-benzoyl-9-(2'-deoxy-β-D-threo-pentofuranosyl)adenine 
• 606141-34-8 [(2R,3S,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]tetrahydrofuran-3-yl] 4-nitrobenzoate 
• 64325-78-6 N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine 
• 13276-53-4 9-(2'-deoxy-β-D-threo-ribofuranosyl)-adenine 

Downstream Products

• 934980-56-0 [(2R,3R,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]tetrahydrofuran-3-yl] methanesulfonate 
• 606141-35-9 N⁶-benzoyl-9-(3',5'-di-O-methylsulfonyl-2'-deoxy-β-D-threo-pentofuranosyl)adenine 
• 125943-99-9 N⁶-benzoyl-3',5'-diazido-2',3',5'-trideoxyadenosine 
• 357399-10-1 N⁶-benzoyl-3',5'-diamino-2',3',5'-trideoxyadenosine 
• 125944-20-9 N⁶-benzoyl-9-(2'-deoxy-β-D-threo-pentofuranosyl)adenine 
• 139290-39-4 N⁶-benzoyl-9-(2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-threo-pentofuranosyl)adenine 3'-(triethylammonium phosphonate) 

Relevant articles and documents

MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF

The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside. An oligomeric compound comprising a modified oligonucleotide consisting of 12-30 linked nucleosides, wherein at least one nucleoside of the modified oligonucleotide is a stereo-non-standard nucleoside; and wherein the oligomeric compound is selected from among an RNAi compound, a modified CRISPR compound, and an artificial mRNA compound.

STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING

The present disclosure provides novel compounds of Formula (I) below. Compounds of the disclosure act as STING modulators/agonists. The present disclosure further relates to methods of synthesis of compounds of Formula (I) and methods of using of compound

9-(2'-Deoxy-β-D-xylofuranosyl)adenine Building Blocks for Solid-Phase Synthesis and Properties of Oligo(2'-deoxy-xylonucleotides)

The 9-(2'-deoxy-β-D-threo-pentofuranosyl)adenine (=9-(2'-deoxy-β-D-xylofuranosyl)adenine, xAd; 2) was protected at its 6-NH2 group with either a benzoyl (5a) or a (dimethylamino)methylidene (6a) residue and with a dimethoxytrityl group at 5'-OH