606141-35-9Relevant academic research and scientific papers
Study on disulfur-backboned nucleic acid: Part 1, efficient synthesis of 3′,5′-dithio-2′-deoxyadenosine
Zheng, Hongchao,Cheng, Changmei,Wang, Hua,Xu, Shanshan,Zhao, Yufen
, p. 2585 - 2587 (2007/10/03)
An efficient procedure is established to synthesize 3′,5′- dithio-2′-deoxyadenosine starting from 2′-deoxyadenosine in five steps in 33% overall yield. In this procedure, the key intermediate 9 was synthesized by twice SN2 reactions with twice
Deoxynucleic guanidine: Synthesis and incorporation of purine nucleosides into positively charged DNG oligonucleotides
Challa, Hemavathi,Bruice, Thomas C.
, p. 1475 - 1481 (2007/10/03)
The synthesis of purine nucleosides capable of making the guanidinium linkage is described for the first time starting from the corresponding 2′-deoxynucleosides. The positively charged mixed base DNG oligomer containing guanine was synthesized on solid-p
Novel and efficient syntheses of 3′,5′-diamino derivatives of 2′,3′,5′-trideoxycytidine and 2′,3′,5′-trideoxyadenosine. Protonation behavior of 3′,5′-diaminonucleosides
Lavandera, Iván,Fernández, Susana,Ferrero, Miguel,Gotor, Vicente
, p. 5449 - 5456 (2007/10/03)
High yielding synthetic routes to 3′,5′-diamino-2′,3′,5′-trideoxycytidine and 3′,5′-diamino-2′,3′,5′-trideoxyadenosine are described. In addition, the protonation behavior of 3′,5′-diamino-2′,3′,5′-trideoxycytidine, 3′,5′-diamino-2′,3′,5′-trideoxyadenosin
