139260-89-2

Upstream product

• 90-80-2 D-Glucono-1,5-lactone 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 139260-88-1 (R)-Benzyloxy-{(4S,5R)-5-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-hydroxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-acetic acid methyl ester 
• 139260-87-0 (R)-{(4R,5R)-5-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-hydroxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-hydroxy-acetic acid methyl ester 
• 100-39-0 benzyl bromide 

Downstream Products

• 139260-90-5 (R)-{(4S,5R)-5-[(S)-1-Acetylamino-2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-benzyloxy-acetic acid methyl ester 
• 139260-91-6 (Z)-(4S,5S)-5-Acetylamino-2-benzyloxy-6-(tert-butyl-diphenyl-silanyloxy)-4-hydroxy-hex-2-enoic acid methyl ester 

Relevant academic research and scientific papers

A new approach to the synthesis of neuraminic acid analogues

2-Alkoxy acrylate derivatives 8 and 11, readily prepared from D-glucono-1,5-lactone by ring opening and β-elimination, are converted into neuraminic acid analogues 9 and 12 via debenzylation and spontaneous cyclization or ring closure via oxymercuration-demercuration, respectively.