1393364-40-3

Upstream product

• 136320-64-4 (2R)-3-[(4-methoxybenzyl)oxy]-2-methylpropanol 
• 132969-71-2 methyl (2S)-[(4-methoxybenzyl)oxy]-2-methylpropanoate 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 132969-60-9 (2S)-3-[(4-methoxybenzyl)oxy]-2-methylpropanal 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 1393364-39-0 tert-butyl(((3S,4S)-5-((4-methoxybenzyl)oxy)-4-methyl-1-(trimethylsilyl)pent-1-yn-3-yl)oxy)dimethylsilane 
• 1393364-32-3 (3S,4S)-5-(4-methoxybenzyloxy)-4-methyl-1-(trimethylsilyl)pent-1-yn-3-ol 

Downstream Products

• 1393364-33-4 tert-butyl(((3S,4S)-5-((4-methoxybenzyl)oxy)-4-methylpent-1-yn-3-yl)oxy)dimethylsilane 
• 1393364-37-8 (4E,6S,8E,10E,12E,14E,16E,18R,19S)-methyl 6,18-bis((tert-butyldimethylsilyl)oxy)-20-((4-methoxybenzyl)oxy)-19-methylicosa-4,8,10,12,14,16-hexaenoate 
• 1393364-38-9 (4E,6S,8E,10E,12E,16E,18E,20R,21S)-methyl 6,20-bis((tert-butyldimethylsilyl)oxy)-22-((4-methoxybenzyl)oxy)-21-methyldocosa-4,8,10,12,16,18-hexaenoate 
• 1395345-63-7 C₃₃H₆₂O₃SiSn 
• 1395345-61-5 C₂₁H₃₄O₃Si 
• 1427351-48-1 C₂₅H₂₇F₃O₅ 
• 1427351-47-0 C₂₅H₂₇F₃O₅ 
• 1395345-59-1 C₁₅H₂₀O₃ 
• 1395345-80-8 C₁₅H₂₀O₃ 

Relevant academic research and scientific papers

Modular synthesis of polyene side chain analogues of the potent macrolide antibiotic etnangien by a flexible coupling strategy based on hetero-bis-metallated alkenes

An efficient procedure for the concise synthesis of hetero-bis-metallated alkenes as useful building blocks for the modular access to highly elaborate polyenes and stabilized analogues is reported. By applying these bifunctional olefins in convergent Stille/Suzuki-Miyaura couplings, novel, carefully selected side chain analogues of the potent RNA polymerase inhibitor etnangien were synthesized by a modular late stage coupling strategy and evaluated for antibacterial and antiproliferative activities. The Royal Society of Chemistry 2013.

Efficient synthesis of diverse hetero-bis-metallated alkenes as modular reagents towards highly conjugated and isolated olefinic systems

An efficient synthesis of diverse hetero-bis-metallated alkenes with conjugated and isolated olefin subunits is reported. Relying on those useful tin/boron reagents a convergent, palladium-catalyzed fragment coupling strategy has been developed as an eleg

Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien

Novel simplified side chains of the potent RNA polymerase inhibitor etnangien were designed, synthesized and evaluated for antibacterial activity against Gram-positive bacteria and one Gram-negative bacterium.