139347-31-2

Upstream product

• 64-18-6 formic acid 
• 139347-09-4 N²-acetyl-5-deazapteroic acid 
• 87373-56-6 2-acetamido-6-formyl-4(3H)-oxopyrido<2,3-d>pyrimidine 
• 150-13-0 4-amino-benzoic acid 

Downstream Products

• 170470-99-2 N(α)-(5-deaza-5,6,7,8-tetrahydropteroyl)-DL-2-amino-4-phosphonobutanoic acid 
• 139347-01-6 N(α)-(5-deazapteroyl)-L-homocysteic acid 
• 141397-59-3 N^α-(5,6,7,8-tetrahydro-5-deazapteroyl)-L-ornithine 
• 139347-12-9 methyl N^α-(N²-acetyl-N¹⁰-formyl-5,6,7,8-tetrahydro-5-deazapteroyl)-N^δ-(benzyloxycarbonyl)-L-ornithinate 
• 139347-10-7 methyl D,L-<(N²acetyl-N¹⁰-formyl-5,6,7,8-tetrahydro-5-deazapteroyl)amino>-4-(diethoxyphosphinyl)butanoate 
• 139347-06-1 2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-pyrido[2,3-d]pyrimidin-6-ylmethyl)-amino]-benzoylamino}-4-(ethoxy-hydroxy-phosphoryl)-butyric acid 
• 866772-95-4 N(α)-(5-deaza-5,6,7,8-tetrahydropteroyl)-L-homocysteic acid 
• 245368-88-1 2-[N-[4-[N-[(2-acetamido-4(3H)oxopyrido[2,3-d]pyrimidin-6-yl)methyl]formamido]benzoyl]amino]-4-nitrobutanoic acid methyl ester 
• 139375-94-3 N-[4-[(2-acetamido-4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-6-yl)methyl]-formamido]benzoic acid 

Relevant academic research and scientific papers

Side chain modified 5-deazafolate and 5-deazatetrahydrofolate analogues as mammalian folylpolyglutamate synthetase and glycinamide ribonucleotide formyltransferase inhibitors: Synthesis and in vitro biological evaluation

5-Deazafolate and 5-deazatetrahydrofolate (DATHF) analogues with the glutamic acid side chain replaced by homocysteic acid (HCysA), 2-amino-4- phosphonobutanoic acid (APBA), and ornithine (Orn) were synthesized as part of a larger program directed toward