139367-20-7Relevant academic research and scientific papers
Synthesis of γ-Hydroxy Ketones by LiClO4-Catalyzed Addition of Lithium Enolates to 1,2-Epoxides
Chini, Marco,Crotti, Paolo,Favero, Lucilla,Pineschi, Mauro
, p. 7583 - 7586 (1991)
A simple, efficient, anti-stereoselective, highly regioselective method is described for the synthesis of γ-hydroxy ketones by the direct opening of 1,2-epoxides with lithium enolates derived from simple ketones in anhydrous THF, in the presence of LiClO4
