Tetrahedron Letters p. 7583 - 7586 (1991)
Update date:2022-08-04
Topics:
Chini, Marco
Crotti, Paolo
Favero, Lucilla
Pineschi, Mauro
A simple, efficient, anti-stereoselective, highly regioselective method is described for the synthesis of γ-hydroxy ketones by the direct opening of 1,2-epoxides with lithium enolates derived from simple ketones in anhydrous THF, in the presence of LiClO4
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