1393803-16-1Relevant articles and documents
SmI2-Mediated intermolecular coupling of γ-lactam N-α-radicals with activated alkenes: Asymmetric synthesis of 11-hydroxylated analogues of the lead compounds CP-734432 and PF-04475270
Hu, Kong-Zhen,Ma, Jie,Qiu, Shi,Zheng, Xiao,Huang, Pei-Qiang
, p. 1790 - 1801 (2013/03/28)
We report, for the first time, the synthesis of 8-aza-analogues of PGE 2. The SmI2-mediated cross coupling reactions of γ-lactam-hemiaminal 9, lactam 2-pyridyl sulfide 17, and lactam 2-pyridyl sulfone 18 with activated alkenes/alkyne