139388-97-9Relevant academic research and scientific papers
SYNTHESIS OF α,β-DISUBSTITUTED ALDEHYDES INVOLVING METALLATED 1-AZA-1,3-BUTADIENES IN THE PRESENCE OF PHOSPHINE COMPLEXES OF PALLADIUM
Dzhemilev, U. M.,Ibragimov, A. G.,Minsker, D. L.,Muslukhov, R. R.,Tolstikov, G. A.
, p. 2050 - 2057 (1991)
A novel catalytic method was developed for the synthesis of α,β-disubstituted aldehydes by the reaction of N-, O-, and S-containing allyl electrophiles with magnesium azaenolates obtained by metallation of α,β-unsaturated imines by Grignard reagents.The reaction is carried out with high regio- and stereoselectivity in the presence of phosphine complexes of palladium.
