1394050-19-1

Basic information

• Product Name: C₂₃H₂₆FNO₄
• Synonyms: C₂₃H₂₆FNO₄
• CAS NO: 1394050-19-1
• Molecular Weight: 399.462
• Mol File: 1394050-19-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₆FNO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₆FNO₄(1394050-19-1)
• EPA Substance Registry System: C₂₃H₂₆FNO₄(1394050-19-1)

Safety Data

• Hazardous Substances Data: 1394050-19-1(Hazardous Substances Data)

Upstream product

• 1394050-18-0 C₂₃H₂₄FNO₄ 
• 1394050-17-9 C₂₅H₂₉FN₂O₃ 
• 1394050-16-8 C₂₂H₂₄FNO₃ 
• 1394050-15-7 [(S)-1-(4-bromobenzyl)-2-(2,2-dimethyl-4,6-dioxo-[1,3]dioxan-5-yl)ethyl]carbamic acid t-butyl ester 
• 1383027-95-9 C₂₀H₂₄BrNO₇ 
• 62561-74-4 (2R)-2-amino-3-(4-bromophenyl)propanoic acid 
• 1383028-06-5 (S)-2-(4-bromobenzyl)-5-oxopyrrolidine-1-carboxylic acid tert-butyl ester 
• 79561-82-3 (2R)-3-(4-bromophenyl)-2-[[(tert-butoxy)carbonyl]amino]propanoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula I: where R1-R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, Z, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.