1394169-29-9

Upstream product

• 183624-93-3 (3R,3aR,6R,6aR)-6-benzyloxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-ol 
• 641-74-7 1,4:3,6-dianhydro-D-mannitol 
• 652-67-5 Isosorbide 
• 829-85-6 diphenylphosphane 
• 72631-67-5 (1R,4S,5R,8R)-8-benzyloxy-2,6-dioxabicyclo<3.3.0>octan-4-ol 
• 1079-66-9 chloro-diphenylphosphine 
• 1394252-03-9 (3R,3aS,6aR)-3-(benzyloxy)-2,3,3a,6a-tetrahydrofuro[3,2-b]furan 
• 1394252-01-7 (3R, 3aR, 6S, 6aS)-6-bromo-hexahydrofuro[3,2-b]furan-3-ol 
• 1394169-21-1 (3R, 3aR, 6S, 6aS)-3-(benzyloxy)-6-bromo-hexahydrofuro[3,2-b]furan 

Relevant academic research and scientific papers

Synthesis of novel chiral monophosphine ligands derived from isomannide and isosorbide. Application to enantioselective hydrogenation of olefins

A new class of monophosphine ligands has been prepared from natural chirality renewable source, 1,4:3,6-dianhydrohexitol compounds, via a nucleophilic substitution process, or a hydrophosphination reaction involving microwave activation. These ligands have been evaluated for the rhodium-catalyzed enantioselective hydrogenation of olefins giving good conversion and enantioselectivity up to 95% and 96% ee, respectively.