1394296-00-4

Upstream product

• 13512-31-7 N-(benzyloxycarbonyl)-L-tyrosine methyl ester 
• 132149-66-7 dimethyl 3,3′-(6,6′-dihydroxybiphenyl-3,3′-diyl)bis[2-(benzyloxycarbonylamino)propanoate] 

Downstream Products

• 1394296-02-6 (2S,2′S)-dimethyl 3,3′-(4,8-dibromodibenzo[d,f ][1,3]dioxepine-2,10-diyl)bis(2-(benzyloxycarbonylamino)propanoate) 
• 1394296-04-8 (2S,2′S)-3,3′-(4,8-dibromodibenzo[d,f][1,3]dioxepine-2,10-diyl)-bis(2-(benzyloxycarbonylamino)propanoic acid) 
• 1394296-06-0 benzyl (2S,2′S)-3,3′-(4,8-dibromodibenzo[d,f][1,3]dioxepine-2,10-diyl)bis(1-(3-bromo-4-hydroxyphenethylamino)-1-oxopropane-3,2-diyl)dicarbamate 
• 1394296-07-1 (2S,2′S)-3,3′-(4,8-dibromodibenzo[d,f][1,3]dioxepine-2,10-diyl)-bis(2-amino-N-(3-bromo-4-hydroxyphenethyl)propanamide) 

Relevant academic research and scientific papers

First total synthesis of dioxepine bastadin 3

The synthesis of dioxepine bastadin 3, a tyrosine-tyramine derivative with a dibenzo-1,3-dioxepine scaffold that is rarely present among natural products, is described. The dibenzo-1,3-dioxepine ring was formed early in the sequence and the (E)-2-(hydroxy