1394356-52-5Relevant articles and documents
Wharton-fragmentation-based approach to the carbocyclic core of the phomoidrides
Murphy, Graham K.,Hama, Naoto,Bedermann, Aaron,Dong, Ping,Schneider, Chris M.,McMahon, Travis C.,Tao, Ran N.,Twenter, Barry M.,Spiegel, David A.,Wood, John L.
, p. 4544 - 4547 (2012/11/06)
The carbocyclic core of the phomoidrides has been synthesized efficiently and in high yield. Key steps include a phenolic oxidation/intramolecular Diels-Alder sequence, tandem radical cyclization, and a late-stage Wharton fragmentation of a densely functionalized isotwistane skeleton.