1394939-75-3

Upstream product

• 1394938-92-1 N-[3-(bromoacetyl)-2-fluorophenyl]-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 
• 1394938-63-6 N-(3-acetyl-2-fluorophenyl)-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 
• 1394939-73-1 2,5-difluoro-N-{2-fluoro-3-[2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-4-yl]phenyl}-N-(methoxymethyl)benzenesulfonamide 
• 1394938-67-0 N-[3-(1-butoxyethenyl)-2-fluorophenyl]-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 
• 1357587-45-1 N-(3-bromo-2-fluorophenyl)-2,5-difluorobenzenesulfonamide 
• 1357587-46-2 N-(3-bromo-2-fluorophenyl)-2,5-difluoro-N-(methoxymethyl)benzenesulfonamide 
• 88571-77-1 tetrahydro-2H-pyran-4-carbothioamide 
• 58534-95-5 3-bromo-2-fluorobenzenamine 
• 344329-76-6 tetrahydro-pyran-4-carboxylic acid amide 
• 110238-91-0 tetrahydropyran-4-carboxylic acid methyl ester 
• 26120-86-5 2,5-difluorobenzenesulfonyl chloride 

Downstream Products

• 1394939-12-8 2,5-difluoro-N-{2-fluoro-3-[5-(pyridin-4-yl)-2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-4-yl]phenyl}-N-(methoxymethyl)benzenesulfonamide 
• 1394938-56-7 N-[2-({4-[4-(3-{[(2,5-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-5-yl]pyridin-2-yl}amino)ethyl]acetamide 
• 1394939-84-4 N-(3-{5-[2-(3-acetylimidazolidin-1-yl)pyridin-4-yl]-2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-4-yl}-2-fluorophenyl)-2,5-difluorobenzenesulfonamide 
• 1394938-55-6 2,5-difluoro-N-{2-fluoro-3-[5-(3-fluoropyridin-4-yl)-2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-4-yl]phenyl}benzenesulfonamide 
• 1394939-80-0 2,5-difluoro-N-{2-fluoro-3-[5-(1-oxidopyridin-4-yl)-2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-4-yl]phenyl}-N-(methoxymethyl)benzenesulfonamide 
• 1394939-82-2 N-[2-({4-[4-(3-{[(2,5-difluorophenyl)sulfonyl](methoxymethyl)amino}-2-fluorophenyl)-2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-5-yl]pyridin-2-yl}amino)ethyl]acetamide 
• 1394939-77-5 2,5-difluoro-N-{2-fluoro-3-[5-(3-fluoropyridin-4-yl)-2-(tetrahydro-2H-pyran-4-yl)-1,3-thiazol-4-yl]phenyl}-N-(methoxymethyl)benzenesulfonamide 

Relevant academic research and scientific papers

THIAZOLYLPHENYL-BENZENESULFONAMIDO DERIVATIVES AS KINASE INHIBITORS

Thiazolylphenyl-benzenesulfonamido derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.

THIAZOLYLPHENYL-BENZENESULFONAMIDO DERIVATIVES AS KINASE INHIBITORS

Thiazolylphenyl-benzenesulfonamido derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.