1395502-76-7Relevant academic research and scientific papers
Synthesis and structure of two new mycolactones isolated from M. ulcerans subsp. shinshuense
Hande, Sudhir M.,Kazumi, Yuko,Lai, W. George,Jackson, Katrina L.,Maeda, Shinji,Kishi, Yoshito
, p. 4618 - 4621 (2012/10/29)
Two new mycolactones, mycolactones S1 and S2, were isolated from culture agar of Mycobacterium ulcerans subsp. shinshuense. Their structures were established in a three-step procedure: (1) probable structures were speculated from MS analysis; (2) candidates were synthesized; (3) HPLC profiles were established for identification of the natural products. Newly isolated mycolactones correspond to the oxidized forms of mycolactone A/B, the causative toxin of Buruli ulcer, isolated from Mycobacterium ulcerans.
