139564-52-6Relevant academic research and scientific papers
CoMFA analysis of the interactions of antipicornavirus compounds in the binding pocket of human rhinovirus-14
Diana,Kowalczyk,Treasurywala,Oglesby,Pevear,Dutko
, p. 1002 - 1008 (1992)
A CoMFA analysis of eight compounds related to disoxaril whose X-ray structures bound to HRV-14 had been determined resulted in a strong positive correlation of activity with steric effects of the compounds, particularly toward the pore end of the compoun
Antipicornavirus Activity of Tetrazole Analogues Related to Disoxaril
Diana, Guy D.,Cutcliffe, David,Volkots, Deborah L.,Mallamo, John P.,Bailey, Thomas R.,et al.
, p. 3240 - 3250 (2007/10/02)
A series of tetrazole analogues of Win 54954, a broad-spectrum antipicornavirus compound, has been synthesized to address the acid lability of the oxazoline ring of this series of compounds.The results of X-ray crystallography studies of several members o
