CoMFA analysis of the interactions of antipicornavirus compounds in the binding pocket of human rhinovirus-14

DOI: 10.1021/jm00084a005

Source and publish data:

Journal of Medicinal Chemistry p. 1002 - 1008 (1992)

Update date:2022-07-29

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Authors:

Diana Diana

Kowalczyk

Treasurywala

Oglesby Oglesby

Pevear Pevear

Dutko Dutko

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Article abstract of DOI:10.1021/jm00084a005

A CoMFA analysis of eight compounds related to disoxaril whose X-ray structures bound to HRV-14 had been determined resulted in a strong positive correlation of activity with steric effects of the compounds, particularly toward the pore end of the compoun

Full text of DOI:10.1021/jm00084a005

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