CoMFA analysis of the interactions of antipicornavirus compounds in the binding pocket of human rhinovirus-14

DOI: 10.1021/jm00084a005

Source and publish data:

Journal of Medicinal Chemistry p. 1002 - 1008 (1992)

Update date:2022-07-29

Topics:

Authors:

Diana Diana

Kowalczyk

Treasurywala

Oglesby Oglesby

Pevear Pevear

Dutko Dutko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00084a005

A CoMFA analysis of eight compounds related to disoxaril whose X-ray structures bound to HRV-14 had been determined resulted in a strong positive correlation of activity with steric effects of the compounds, particularly toward the pore end of the compoun

Full text of DOI:10.1021/jm00084a005

Products guided by the article

Product name:2-(5-{5-[2,6-Dimethyl-4-(2-methyl-2H-tetrazol-5-yl)-phenoxy]-pentyl}-isoxazol-3-ylmethoxymethoxy)-ethanol

Cas No:139564-52-6

R&D Labs maybe for 139564-52-6

Jinan Decheng Hemu Medical Technology Co.，Ltd.

Contact:+86-531-68650525

Address:NO.554 Zhengfeng Road High-new Technology Development Zone
Yicheng Goto Pharmaceuticals Co.,Ltd.

Contact:+86 710 3423122

Address:5th Floor,East Gate of Building #2,Servo-Industrial Park,1st Qilin Road,Xiangyang,Hubei,China
GLD peptide scientific lnc.

Contact:21-7631221 15884421033

Address:326 Science and technology,Shanghai,China
Jinan Jianfeng Chemical Co., Ltd

Contact:0086-531-88110457

Address:sales01(-a-t-)pharmachemm{dot}c+o+m
Maithili Life Sciences

Contact:+91 9963263336

Address:Plot#146A, IDA Mallapur, Hyderabad - 500072

Relevant to this article

Pheromone synthesis. Part 253: Synthesis of the racemates and enantiomers of triglycerides of male Drosophila fruit flies with special emphasis on the preparation of enantiomerically pure 1-monoglycerides

Doi:10.1016/j.tet.2012.07.086
(2012)
Identification of antitubercular benzothiazinone compounds by ligand-based design

Doi:10.1021/jm3008882
(2012)
Heterocyclization of N-(1-chloro-2,2,2-trifluoroethylidene)carbamates with β-enaminoesters - A novel synthetic strategy to functionalized trifluoromethylated pyrimidines

Doi:10.1016/j.tet.2012.07.099
(2012)
Stereochemically controlled competitive cyclisations with phenylthio migration in the synthesis of cyclic ethers

Doi:10.1016/S0040-4039(00)93990-X
(1992)
New 2-methylisothiazolones

Doi:10.1002/jhet.5570370610
(2000)
Copper-mediated trifluoromethylation of α-diazo esters with TMSCF₃: The important role of water as a promoter

Doi:10.1021/ja307058c
(2012)

Article Doi