139580-07-7

Basic information

• Product Name: [Bis-(4-methoxy-phenyl)-methyl]-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-eth-(E)-ylidene]-amine
• Synonyms: [Bis-(4-methoxy-phenyl)-methyl]-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-eth-(E)-ylidene]-amine
• CAS NO: 139580-07-7
• Molecular Weight: 475.703
• Mol File: 139580-07-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [Bis-(4-methoxy-phenyl)-methyl]-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-eth-(E)-ylidene]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [Bis-(4-methoxy-phenyl)-methyl]-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-eth-(E)-ylidene]-amine(139580-07-7)
• EPA Substance Registry System: [Bis-(4-methoxy-phenyl)-methyl]-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-eth-(E)-ylidene]-amine(139580-07-7)

Safety Data

• Hazardous Substances Data: 139580-07-7(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 133187-21-0 Methyl (S)-(+)-α-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-α-phenylacetate 
• 21210-43-5 (S)-Methyl mandelate 
• 19293-62-0 p,p'-dimethoxybenzhydrylamine 
• 133187-22-1 (2S)-2-(tert-butyldimethylsilyloxy)-2-phenylacetaldehyde 

Downstream Products

• 130115-09-2 (3S,4S)-3-Benzyloxy-1-[bis-(4-methoxy-phenyl)-methyl]-4-[(S)-(tert-butyl-dimethyl-silanyloxy)-phenyl-methyl]-azetidin-2-one 
• 130193-82-7 (3R,4R)-3-Benzyloxy-1-[bis-(4-methoxy-phenyl)-methyl]-4-[(S)-(tert-butyl-dimethyl-silanyloxy)-phenyl-methyl]-azetidin-2-one 
• 130115-05-8 (2S,3R)-3-Amino-2-hydroxy-4-phenyl-butyric acid isopropyl ester 
• 130115-12-7 (S)-Benzyloxy-((4R,5S)-2-oxo-5-phenyl-oxazolidin-4-yl)-acetic acid isopropyl ester 
• 128223-55-2 (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoic acid hydrochloride 
• 130115-10-5 (2S,3R,4R)-3-Amino-2-benzyloxy-4-hydroxy-4-phenyl-butyric acid isopropyl ester 
• 130115-10-5 (2S,3R,4S)-3-Amino-2-benzyloxy-4-hydroxy-4-phenyl-butyric acid isopropyl ester 
• 59554-14-2 (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoic acid 

Relevant articles and documents

A Stereoselective Synthesis of the (2R,3S)- and (2S,3R)-3-Amino-2-hydroxybutyric Acid Derivatives, the Key Components of a Renin Inhibitor and Bestatin

The title synthesis was achieved by featuring the -cycloaddition reaction of benzyloxyketene with a chiral imine derived from methyl (R)- or (S)-mandelate, alcoholysis of the formed 3,4-cis disubstituted β-lactam under acidic conditions, and reductiv