128223-55-2

Basic information

• Product Name: (2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRIC ACID HYDROCHLORIDE
• Synonyms: (2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRIC ACID HYDROCHLORIDE;(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID HCL;(2S,3R)-3-aMino-2-hydroxy-4-phenylbutanoic acid hydrochloride;(2S,3R)-AHPA;Benzenebutanoic acid, .beta.-amino-.alpha.-hydroxy-, hydrochloride (1:1), (.alpha.S,.beta.R)-;(2R,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid≥ 95% (HPLC);Benzenebutanoic acid, β-amino-α-hydroxy-, hydrochloride (1:1), (αS,βR)-
• CAS NO: 128223-55-2
• Molecular Formula: C₁₀H₁₃NO₃*ClH
• Molecular Weight: 231.68
• Product Categories: A - H;Amino Acids;Modified Amino Acids
• Mol File: 128223-55-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 428.5 °C at 760 mmHg
• Flash Point: 213 °C
• Appearance: /
• Vapor Pressure: 4.17E-08mmHg at 25°C
• Storage Temp.: −20°C
• CAS DataBase Reference: (2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRIC ACID HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRIC ACID HYDROCHLORIDE(128223-55-2)
• EPA Substance Registry System: (2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRIC ACID HYDROCHLORIDE(128223-55-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 128223-55-2(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C10H13NO3.ClH/c11-8(9(12)10(13)14)6-7-4-2-1-3-5-7;/h1-5,8-9,12H,6,11H2,(H,13,14);1H/t8-,9+;/m1./s1

Upstream product

• 115186-33-9 (R)-tert-butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate 
• 18942-49-9 Boc-D-Phe-OH 
• 77119-85-8 N-(tert-butoxycarbonyl)-D-phenylalaninal 
• 128223-46-1 methyl (R)-N-(isopropoxycarbonyl)phenylalaninate 
• 128223-47-2 (R)-N-(isopropoxycarbonyl)phenylalaninol 
• 129867-98-7 (R)-N-(isopropoxycarbonyl)phenylalaninal 
• 13033-84-6 D-phenylalanine methyl ester hydrochloride 
• 673-06-3 D-(R)-phenylalanine 
• 129867-99-8 (3-R)-2-acetoxy-3-isopropoxycarbonylamino-4-phenylbutyronitrile 
• 130115-10-5 (2S,3R,4R)-3-Amino-2-benzyloxy-4-hydroxy-4-phenyl-butyric acid isopropyl ester 
• 130115-09-2 (3S,4S)-3-Benzyloxy-1-[bis-(4-methoxy-phenyl)-methyl]-4-[(S)-(tert-butyl-dimethyl-silanyloxy)-phenyl-methyl]-azetidin-2-one 
• 130115-12-7 (S)-Benzyloxy-((4R,5S)-2-oxo-5-phenyl-oxazolidin-4-yl)-acetic acid isopropyl ester 
• 139580-07-7 [Bis-(4-methoxy-phenyl)-methyl]-[(S)-2-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-eth-(E)-ylidene]-amine 
• 133187-21-0 Methyl (S)-(+)-α-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-α-phenylacetate 

Downstream Products

• 1356606-78-4 (R)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-2-hydroxy-4-phenylbutanoic acid 
• 1455093-39-6 (2S,3R)-methyl 3-(1-cyano-4-hydroxy-7-phenoxyisoquinoline-3-carboxamido)-2-hydroxy-4-phenylbutanoate 
• 1455088-49-9 (2S,3R)-methyl 3-(1-cyano-4-hydroxy-7-phenoxyisoquinoline-3-carboxamido)-2-hydroxy-4-phenylbutanoic acid 
• 140409-03-6 methyl (2R,3R)-2-acetoxy-3-acetylamino-4-phenylbutyrate 
• 140409-02-5 methyl (2S,3R)-2-acetoxy-3-acetylamino-4-phenylbutyrate 

Relevant articles and documents

Anti- and syn-selective cyanosilylation reactions promoted by a sugar-based bifunctional catalyst: Stereoselective syntheses of essential building blocks for HIV protease inhibitors and bestatin

Chiral bifunctional catalyst 6 promoted anti- and syn-selective cyanosilylation reactions from chiral amino aldehydes derived from phenylalanine in excellent yields. Thus, from dibenzyl protected amino aldehyde 9, syn isomer was obtained as the major prod

Preparation of α-hydroxy-β-Fmoc amino acids from N-Boc amino acids

A general method for the conversion of N-Boc amino acids into their homologated α-hydroxy-β-Fmoc amino acids is described. The protocol involved preparation of the amino aldehyde by reduction of the corresponding Weinreb amides, hydrocyanation, and hydrol

A Practical Synthesis of threo-3-Amino-2-hydroxycarboxylic Acids

An expeditious synthesis of (2R,3S)-3-amino-4-cyclohexyl-2-hydroxybutyric acid (2) and (2S,3R)-3-amino-2-hydroxy-4-phenylbutyric acid (4), the key components of the renin inhibitor (1) and bestatin (3), respectively, have been accomplished by featuring hi