1395882-30-0

Basic information

• Product Name: C₂₈H₂₇ClF₂N₆O₄
• Synonyms: C₂₈H₂₇ClF₂N₆O₄
• CAS NO: 1395882-30-0
• Molecular Weight: 585.01
• Mol File: 1395882-30-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₂₇ClF₂N₆O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₂₇ClF₂N₆O₄(1395882-30-0)
• EPA Substance Registry System: C₂₈H₂₇ClF₂N₆O₄(1395882-30-0)

Safety Data

• Hazardous Substances Data: 1395882-30-0(Hazardous Substances Data)

Upstream product

• 462-06-6 fluorobenzene 
• 105956-97-6 clinafloxacin 
• 168009-79-8 1-[2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole 

Relevant articles and documents

Design, synthesis and evaluation of clinafloxacin triazole hybrids as a new type of antibacterial and antifungal agents

A series of clinafloxacin triazole hybrids as a new type of antibacterial and antifungal agents were synthesized for the first time and screened for their antimicrobial efficacy against four Gram-positive bacteria, four Gram-negative bacteria and two fungi by two fold serial dilution technique. The bioactive assay indicated that most of the target compounds displayed broad antimicrobial spectrum and good antibacterial and antifungal activities with low MIC values ranging from 0.25 to 2 μg/mL against all the tested strains which exhibited comparable or even better efficiency in comparison with the reference drugs Chloramphenicol, Clinafloxacin and Fluconazole, respectively. Notably, some synthesized clinafloxacin triazoles showed stronger efficacy against methicillin-resistant Staphylococcus aureus than their parent Clinafloxacin.