139619-03-7

Basic information

• Product Name: 1-methyl-4-pyridinium iodide
• Synonyms: 1-methyl-4-pyridinium iodide
• CAS NO: 139619-03-7
• Molecular Weight: 338.191
• Mol File: 139619-03-7.mol

Chemical Properties

• CAS DataBase Reference: 1-methyl-4-pyridinium iodide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-4-pyridinium iodide(139619-03-7)
• EPA Substance Registry System: 1-methyl-4-pyridinium iodide(139619-03-7)

Safety Data

• Hazardous Substances Data: 139619-03-7(Hazardous Substances Data)

Upstream product

• 25565-20-2 trans-1-methyl-4-<4-nitrostyryl>-pyridinium iodide 
• 32597-98-1 4-(2-pyridin-4-yl-vinyl)phenylamine 
• 540-37-4 p-aminoiodobenzene 
• 1193501-28-8 4-[2-(4-azidophenyl)vinyl]-1-methylpyridinium iodide 
• 1193501-32-4 4-[2-(4-azidophenyl)vinyl]pyridine 
• 100-43-6 4-vinylpyridine 
• 106-40-1 4-bromo-aniline 
• 556-18-3 4-aminobenzaldehyde 
• 2301-80-6 N-methyl-4-methylpyridinium iodide 
• 101645-12-9 trans-4-pyridine 
• 74-88-4 methyl iodide 

Relevant articles and documents

Influence of solvent polarity and medium acidity on the UV-Vis spectral behavior of 1-methyl-4-[4-amino-styryl] pyridinum iodide

Electronic absorption, and excitation spectra of 1-methyl-4-[4-aminostyryl] pyridinum iodide (M-NH2) were measured in solvents of different polarity. The (M-NH2) dye exhibits negative solvatochromism, i.e. a hypsochromic band shift as the solvent polarity increases. The fluorescence quantum yield is also sensitive to the polarity and viscosity of the medium. The ground and excited state protonation constants were calculated and amount to 3.35 and 0.62, respectively. The effect of micellization on the emission spectrum of (M-NH2) are also studied in sodium dodecyl sulphate (SDS). The fluorescence intensity increases as the concentration of SDS increases with an abrupt change at cmc. The quantum yield of the cis trans photoisomerization is also determined in aqueous buffer solution of pH 1.1.

Water-soluble small-molecule probes for RNA based on a two-photon fluorescence "off-on" process: Systematic analysis in live cell imaging and understanding of structure-activity relationships

The conveniently obtained water-soluble small-molecule L1-5 were selective for RNA with remarkable "off-on" two-photon fluorescence responses in vitro and in vivo, showing that L1-5 can surprisingly stain mitochondria or nucleoli individually with orange

Azido push-pull fluorogens photoactivate to produce bright fluorescent labels

Dark azido push-pull chromophores have the ability to be photoactivated to produce bright fluorescent labels suitable for single-molecule imaging. Upon illumination, the aryl azide functionality in the fluorogens participates in a photochemical conversion to an aryl amine, thus restoring charge-transfer absorption and fluorescence. Previously, we reported that one compound, DCDHF-V-P-azide, was photoactivatable. Here, we demonstrate that the azide-to-amine photoactivation process is generally applicable to a variety of push-pull chromophores, and we characterize the photophysical parameters including photoconversion quantum yield, photostability, and turn-on ratio. Azido push-pull fluorogens provide a new class of photoactivatable singlemolecule probes for fluorescent labeling and super-resolution microscopy. Lastly, we demonstrate that photoactivated push-pull dyes can insert into bonds of nearby biomolecules, simultaneously forming a covalent bond and becoming fluorescent (fluorogenic photoaffinity labeling).