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5-fluoro-6-ethoxy-5,6-dihydrouracil is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 13964-48-2 Structure
  • Basic information

    1. Product Name: 5-fluoro-6-ethoxy-5,6-dihydrouracil
    2. Synonyms: 5-fluoro-6-ethoxy-5,6-dihydrouracil
    3. CAS NO:13964-48-2
    4. Molecular Formula:
    5. Molecular Weight: 176.147
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 13964-48-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-fluoro-6-ethoxy-5,6-dihydrouracil(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-fluoro-6-ethoxy-5,6-dihydrouracil(13964-48-2)
    11. EPA Substance Registry System: 5-fluoro-6-ethoxy-5,6-dihydrouracil(13964-48-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 13964-48-2(Hazardous Substances Data)

13964-48-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 13964-48-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,6 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13964-48:
(7*1)+(6*3)+(5*9)+(4*6)+(3*4)+(2*4)+(1*8)=122
122 % 10 = 2
So 13964-48-2 is a valid CAS Registry Number.

13964-48-2Relevant articles and documents

Fluorinated Pyrimidines. Part 4. Synthesis, Properties and Stereochemical Conversion of the cis and trans Isomers of 6-Alkoxy-5-fluoro-5,6-dihydrouracils

Visser, Gerard W. M.,Wedzinga, Rinny,Klok, Robert P.,Herscheid, Jacobus D. M.

, p. 231 - 236 (2007/10/02)

The reaction of 6-acetoxy-5-fluoro-5,6-dihydrouracil with ROH (R=Me, Et, Pr, Pri, Bu, But) under acidic conditions has been investigated using 18F as a tracer.The quantitative replacement of the OAc-group proceeded predominantly with cisoid (gauche) stereochemistry, but upon prolonged heating the amount of the trans compound increased.This isomerization did not originate from epimerization at C5.The trans compounds-apart from being more stable towards substitution and elimination than the corresponding cis compounds-gave invariably substitution products with inversion of configuration, while the cis compounds mainly retained their configuration.Within the concept of the unifying ion-pair mechanism it is proposed that the trans compound reacts via an intimate protonated intermediate and the cis compound via a solvent-separated protonated intermediate.As a result, it was not the gauche attraction between the fluorine atom and the incoming nucleophile, but the poor ?-donor ability of the C-F bond that was the determining factor in the cisoid stereochemistry of 5-fluoro-5,6-dihydrouracil adducts.

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