1396790-06-9Relevant academic research and scientific papers
Rhodium-catalyzed ortho C-H bond activation of arylamines for the synthesis of quinoline carboxylates
Gadakh, Sunita K.,Dey, Soumen,Sudalai
, p. 2969 - 2977 (2016/03/12)
The rhodium catalyzed annulation of anilines with alkynic esters allowing for the high-yield synthesis of quinoline carboxylates with excellent regioselectivity is described. This unprecedented reaction employs either formic acid as the C1 source and reductant or copper(ii) as the oxidant and is proposed to proceed via rhodacycle of in situ generated amide and enamine ester followed by ortho C-H activation of arylamines with rhodium as the catalyst.
Bromination of 4,6-dimethoxyindoles
Mitchell, Peter S.R.,Sengul, Ibrahim F.,Kandemir, Hakan,Nugent, Stephen J.,Chen, Rui,Bowyer, Paul K.,Kumar, Naresh,Black, David Stc.
, p. 8163 - 8171 (2012/09/22)
The bromination of activated 4,6-dimethoxyindoles can be carried out effectively provided that an electron-withdrawing group is also present. Thus the range of products includes 2-bromo-7-formyl or 2-bromo-7-acetylindoles 13a-c and 16, 7-bromo-2-acetylind
