139685-47-5Relevant academic research and scientific papers
Proton and carbon-13 nuclear magnetic resonance spectroscopy of diastereoisomeric 3- and 17β-tetrahydropyranyl ether derivatives of estrone and estradiol
Boucheau, Vincent,Renaud, Melanie,Ravel, Marc Rolland de,Mappus, Elisabeth,Cuilleron, Claude Y.
, p. 209 - 221 (1990)
Protection of 3- and 17β-hydroxyl groups of estrone and estradiol as tetrahydropyranyl ether derivatives led to mixtures of 2'(R)- and 2'(S)-diastereoisomers which were separated by crystallization (3-tetrahydropyranyl ethers), or by thin layer chromatogr
Sulfuric acid adsorbed on silica gel. An efficient catalyst for the tetrahydropyranylation of alcohols
Chavez,Godinez
, p. 159 - 164 (2007/10/02)
Sulfuric acid adsorbed on silica gel is an efficient catalyst for the tetrahydropyranylation of alcohols and phenols. The reaction takes 1 to 10 minutes to be completed and nearly quantitative yields are obtained. The method is remarkable simple and inexpensive.
