139689-16-0

Basic information

• Product Name: 1H-3-Benzazepine, 6-bromo-2,3,4,5-tetrahydro-7,8-dimethoxy-1-phenyl-3-(2-propenyl)-, (R)-
• CAS NO: 139689-16-0
• Molecular Formula: C21H24BrNO2
• Molecular Weight: 402.331
• Mol File: 139689-16-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-3-Benzazepine, 6-bromo-2,3,4,5-tetrahydro-7,8-dimethoxy-1-phenyl-3-(2-propenyl)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-3-Benzazepine, 6-bromo-2,3,4,5-tetrahydro-7,8-dimethoxy-1-phenyl-3-(2-propenyl)-, (R)-(139689-16-0)
• EPA Substance Registry System: 1H-3-Benzazepine, 6-bromo-2,3,4,5-tetrahydro-7,8-dimethoxy-1-phenyl-3-(2-propenyl)-, (R)-(139689-16-0)

Safety Data

• Hazardous Substances Data: 139689-16-0(Hazardous Substances Data)

Upstream product

• 139689-14-8 (R)-(+)-6-bromo-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine 
• 106-95-6 allyl bromide 
• 20569-49-7 7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine 
• 20012-08-2 1-phenyl-N-methyl-7,8-dimethoxy-1,2,4,5-tetrahydro-3H-benzazepine 
• 56030-50-3 (+)-(R)-1-phenyl-N-methyl-7,8-dimethoxy-1,2,4,5-tetrahydro-3H-benzazepine 
• 62717-90-2 (1R)-(+)-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine 

Downstream Products

• 139689-19-3 (+)-6-Br-APB hydrobromide 

Relevant articles and documents

Stereoisomeric probes for the D1 dopamine receptor: synthesis and characterization of R-(+) and S-(-) enantiomers of 3-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine and its 6-bromo analogue.

Substituted 1-phenyl-3-benzazepines (e.g., SKF 38393 and fenoldopam) exhibit stereoselectivity in moderately high-affinity binding to and partial agonist activation of D1 dopamine receptors. The 3-allyl (APB) and the 3-allyl-6-chloro (6-Cl-APB) analogues