139741-42-7

Basic information

• Product Name: 2-Benzyloxy-6-oxo-4-trifluoromethyl-5,6-dihydro-4H-[1,3]oxazine-4-carboxylic acid methyl ester
• Synonyms: 2-Benzyloxy-6-oxo-4-trifluoromethyl-5,6-dihydro-4H-[1,3]oxazine-4-carboxylic acid methyl ester
• CAS NO: 139741-42-7
• Molecular Weight: 331.248
• Mol File: 139741-42-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Benzyloxy-6-oxo-4-trifluoromethyl-5,6-dihydro-4H-[1,3]oxazine-4-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzyloxy-6-oxo-4-trifluoromethyl-5,6-dihydro-4H-[1,3]oxazine-4-carboxylic acid methyl ester(139741-42-7)
• EPA Substance Registry System: 2-Benzyloxy-6-oxo-4-trifluoromethyl-5,6-dihydro-4H-[1,3]oxazine-4-carboxylic acid methyl ester(139741-42-7)

Safety Data

• Hazardous Substances Data: 139741-42-7(Hazardous Substances Data)

Upstream product

• 128970-26-3 methyl 2-benzyloxycarbonylimino-3,3,3-trifluoropropionate 
• 75-36-5 acetyl chloride 

Downstream Products

• 139741-47-2 tert-butyl 2-(3-benzyloxycarbonylamino-3-trifluoromethylpyrrolidin-2,5-dion-1-yl)-propionate 
• 139741-45-0 tert-butyl N-benzyloxycarbonyl-2-trifluoromethyl-β-aspartyl-(α-methylester)-S-alaninate 
• 139741-51-8 benzyl N-benzyloxycarbonyl-S-2-trifluoromethyl-β-aspartyl-(α-methylester)-S-prolinate 
• 139741-51-8 benzyl N-benzyloxycarbonyl-R-2-trifluoromethyl-β-aspartyl-(α-methylester)-S-prolinate 
• 208192-90-9 (S)-2-Benzyloxycarbonylamino-N-((2R,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yl)-2-trifluoromethyl-succinamic acid methyl ester 
• 139741-53-0 methyl 2-trifluoromethyl-β-aspartyl-(α-methylester)-S-phenylalaninate 
• 208192-95-4 (S)-2-Benzyloxycarbonylamino-N-((2R,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-acetylamino-tetrahydro-pyran-2-yl)-2-trifluoromethyl-succinamic acid methyl ester 
• 139741-43-8 1-benzyl-3-benzyloxycarbonylamino-3-trifluoromethylpyrrolidine-2,5-dione 
• 129398-30-7 2-Benzyloxycarbonylamino-2-trifluoromethyl-succinic acid 1-methyl ester 
• 139741-49-4 methyl N-benzyloxycarbonyl-2-trifluoromethyl-β-aspartyl-(α-methylester)-S-phenylalaninate 

Relevant articles and documents

A New Convenient Synthesis of 2-Trifluoromethyl Substituted Aspartic Acid and its Isopeptides. Part 11

The reaction of methyl 2-benzyloxycarbonylimino-3,3,3-trifluoropropionate with acetyl chloride-triethylamine yields methyl 2-benzyloxy-6-oxo-4,5-dihydro-4-trifluoromethyl-1,3-oxazine-4-carboxylate, a β-activated equivalent for 2-trifluoromethyl substitute