1397683-79-2

Basic information

• Product Name: 1H-Pyrazole-3,5-dicarboxaMide
• Synonyms: 1H-Pyrazole-3,5-dicarboxaMide;1H-Pyrazole-3,5-dicarboxylic acid diamide
• CAS NO: 1397683-79-2
• Molecular Formula: C₅H₆N₄O₂
• Molecular Weight: 154.12674
• Mol File: 1397683-79-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-Pyrazole-3,5-dicarboxaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-3,5-dicarboxaMide(1397683-79-2)
• EPA Substance Registry System: 1H-Pyrazole-3,5-dicarboxaMide(1397683-79-2)

Safety Data

• Hazardous Substances Data: 1397683-79-2(Hazardous Substances Data)

Usage

General Description

1H-Pyrazole-3,5-dicarboxamide is a chemical compound that belongs to the class of pyrazoles, which are a group of organic compounds with a five-membered ring containing two nitrogen atoms and three carbon atoms. This specific compound is a dicarboxamide derivative of pyrazole, meaning it contains two carboxamide functional groups. It has potential applications in pharmaceutical and agricultural industries, where it may be used in the synthesis of various drugs and agrochemicals. Additionally, it may exhibit biological activities and can be used as a building block for the development of new compounds with diverse properties. Its chemical structure and properties make it a valuable component in the field of organic chemistry and drug discovery.

Upstream product

• 37687-24-4 diethyl 1H-pyrazole-3,5-dicarboxylate 
• 148832-75-1 3,5-(1H)-pyrazoledicarbaldehyde 
• 4077-76-3 3,5-dicarbomethoxypyrazole 

Downstream Products

• 144693-57-2 bis(3,5-aminomethyl)pyrazole 
• 847573-68-6 1H-pyrazole-3,5-dicarbonitrile 

Relevant articles and documents

Ru-based complexes as heterogeneous potential catalysts for the amidation of aldehydes and nitriles in neat water

Five novel heterogeneous mononuclear complex-anchored Ru(III) have been efficiently sono-synthesized and characterized by utilizing several analytical techniques. The assembled complexes could be utilized as effective, robust and recyclable (up to eight consecutive runs) catalysts for one-pot transformation of a vast array of nitriles and aldehydes to primary amides in H2O under aerobic conditions. Moreover, some unreported di- and tetra-amide derivatives were obtained also under the optimal conditions. The results of ICP/OES analysis demonstrated that there is no detected leaching of the recycled catalyst, which suggests the real heterogeneity of the present protocol. The present Ru-complexes exhibited superiority compared to other reported catalysts for amide preparation in terms of low catalyst load, short reaction time, low operating temperature, no hazardous additives required, and high values of TON (990) and TOF (1980 h11).

6,7-DIHYDRO-PYRAZOLO[1,5-A]PYRAZIN-4-YLAMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)

The present invention relates to novel 6,7-dihydro-pyrazolo[1,5-a]pyrazin-4-yl-amine derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACEl, Asp2, or memapsin2. The invention is also directed to pharmaceu