1398229-59-8

Basic information

• Product Name: 2-(((2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)methyl)thio)pyrimidine-4,6-diamine
• Synonyms: 2-(((2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)methyl)thio)pyrimidine-4,6-diamine
• CAS NO: 1398229-59-8
• Molecular Weight: 421.52
• Mol File: 1398229-59-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(((2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)methyl)thio)pyrimidine-4,6-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(((2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)methyl)thio)pyrimidine-4,6-diamine(1398229-59-8)
• EPA Substance Registry System: 2-(((2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)methyl)thio)pyrimidine-4,6-diamine(1398229-59-8)

Safety Data

• Hazardous Substances Data: 1398229-59-8(Hazardous Substances Data)

Upstream product

• 1398230-14-2 4-(bromomethyl)-2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazole 
• 1004-39-3 4,6-diamino-2-mercaptopyrimidine 
• 1398230-06-2 (2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)methanol 
• 1398229-82-7 3-(2-fluoroethoxy)-4-methoxybenzonitrile 
• 1004-39-3 4,6-diaminopyrimidine-2(1H)-thione 
• 1398229-98-5 ethyl 2-(3-(2-Fluoroethoxy)-4-methoxyphenyl)-5-methylthiazole-4-carboxylate 
• 1398229-90-7 3-(2-fluoroethoxy)-4-methoxybenzothioamide 
• 52805-46-6 2-methoxy-5-cyanophenol 

Relevant articles and documents

DEOXYCYTIDINE KINASE INHIBITORS

Provided herein are compounds that bind to dCK and methods for treating cancer.

DEOXYCYTIDINE KINASE BINDING COMPOUNDS

The invention provides compounds that bind to deoxycytidine kinase (dCK) and compositions including pharmaceutically acceptable compositions containing the compounds. The compounds are useful in treating diseases and disorders where dCK activity is implicated such as cancer and immune disorders. The compounds also find use in clinical methodologies including positron emission tomography (PET) imaging.