13985-56-3

Usage

Uses

Used in Chemical Synthesis Industry:
2-Ethyl-1,3-dinitrobenzene is used as a chemical intermediate for the production of various aromatic compounds and dyes. Its unique structure allows it to be a key component in the creation of a range of colorants and specialty chemicals that find applications in different industries.
Used in Pesticide Formulation:
In the agricultural sector, 2-Ethyl-1,3-dinitrobenzene is utilized as a pesticide. It contributes to the development of products designed to control, repel, or kill pests that can damage crops and affect agricultural productivity. The use of 2-ethyl-1,3-dinitrobenzene in pesticides underscores its potential as an effective tool in integrated pest management strategies.

InChI:InChI=1/C8H8N2O4/c1-2-6-7(9(11)12)4-3-5-8(6)10(13)14/h3-5H,2H2,1H3

Upstream product

• 100-41-4 ethylbenzene 
• 702642-25-9 4-ethyl-3,5-dinitrobenzeneamine 
• 13985-60-9 2-ethyl-1,3,5-trinitrobenzene 
• 619-64-7 p-ethylbenzoic acid 
• 477953-15-4 4-ethyl-3,5-dinitro-benzoic acid 

Downstream Products

• 603-12-3 2,6-dinitrobenzoic acid 
• 90007-09-3 2-ethyl-3-nitrobenzeneamine 
• 477953-17-6 8-ethyl-7-isothiocyanato-quinoline 
• 702642-37-3 2-(2-iodo-6-nitrophenyl)propan-1-ol 
• 702642-35-1 2-(2-bromo-6-nitrophenyl)propan-1-ol 
• 702642-19-1 2-ethyl-1-iodo-3-nitrobenzene 
• 189216-59-9 5'-O-[2-(o-nitrophenyl)prop-1-yloxycarbonyl]thymidine 
• 298699-71-5 3'-O-{[2-(2-nitrophenyl)propoxy]carbonyl}thymidine 
• 179691-31-7 2-(2-nitrophenyl)propyl chloroformate 
• 64987-77-5 2-(2-nitrophenyl)propanol 
• 702642-17-9 1-bromo-2-ethyl-3-nitrobenzene 
• 702642-41-9 2-(2,6-dinitrophenyl)propan-1-ol 
• 2095-05-8 2-ethyl-m-phenylenediamine 

Relevant academic research and scientific papers

NITRATION OF AROMATIC COMPOUNDS

The present invention provides a process for nitrating aromatic compounds without the need for a solid catalyst and/or any organic solvents and/or any other additives. A typical process includes combining or admixing a nitric acid and an anhydride compound under conditions sufficient to produce a reactive intermediate. The aromatic compound to be nitrated is then added to this reactive intermediate to produce a nitroaromatic compound. The nitroaromatic compound can be substituted with one or more, typically, one to three, and often one or two nitrate (-NO2) groups.

New Types of Very Efficient Photolabile Protecting Groups Based upon the [2-(2-Nitrophenyl)propoxy]carbonyl (NPPOC) Moiety

Based upon the photolabile [2-(2-nitrophenyl)propoxy]carbonyl group (NPPOC), a large number of modified 2-(2-nitrophenyl)propanol derivatives substituted at the phenyl ring (see 23-34 and 57-76) as well as at the side-chain (see 85-92 and 95-98) were synthesized to improve the photoreactivity of this new type of photolabile entity. The phenyl moiety was also exchanged by the naphthalenyl group (see 102, 103, 105, 108, 110, 113, and 114), the thienyl substituent (see 115, 117, 118, and 120), and the benzothienyl substituent (see 121). The 2-(2-nitroaryl- and heteroaryl) propanols were converted with diphosgene into the corresponding carbonochloridates, which reacted subsequently with thymidine to the thymidine 5′-(protected carbonates) 123-178 as the main reaction products. In several cases, the corresponding 3′-carbonates and 3′,5′ -dicarbonates 179-212 were also isolated and characterized. Photolysis studies under standardized conditions (see Table) indicated that the rate of photocleavage varies in a broad range depending on the substituents. So far, the thymidine 5′-[2-(5-halo-2-nitrophenyl)propyl carbonates] 127-129, 5′-[2-(nitro[1,1′-biphenyl]3-yl)propyl carbonates] 136-139, 5′-{2-[2-nitro-5-(thianthren-1-yl)phenyl]propyl carbonate} (140), 5′-[2-(5-naphthalenyl-2-nitrophenyl)propyl carbonates] 141 and 142, and 5′-[2-(2-nitro-5-thienylphenyl)propyl carbonates] 143 and 144 showed the best properties regarding fast and uniform deprotection. Since the nucleobases of 213-215 do not influence the photocleavage features, in general, the new type of photolabile building blocks allows in form of their 3′ -phosphoramidites the photolithographic formation of high-quality biochips.

Preparation of 8-alkyl 7-(2-imidazolinylamino)quinolines via palladium mediated alkylations

A convenient preparation of 8-alkyl substituted 7-(2-imidazo linylamino)quinolines from the corresponding 8-trifluoro-methanesulfonates, utilizing palladium cross-coupling reactions is described.