139888-79-2Relevant academic research and scientific papers
Intramolecular Diels-Alder reactions of diester-tethered trienes. Synthesis of medium ring-containing carbocycles and heterocycles
Craig, Donald,Ford, Mark J.,Gordon, Richard S.,Stones, James A.,White, Andrew J. P.,Williams, David J.
, p. 15045 - 15066 (1999)
Intramolecular Diels-Alder reactions of cyclohexane-1,2- dicarboxylic anhydride-derived diester-tethered trienes are described. The stereoselectivities of most of the cycloaddition processes studied may be rationalised in terms of an preferred 'inside'-oriented diene giving rise to an endo-transition state.
Anti and syn glycolate aldol reactions with a readily displaced thiol auxiliary
Fanjul, Sandra,Hulme, Alison N.
experimental part, p. 9788 - 9791 (2009/04/07)
(Chemical Equation Presented) The TBDPS protected glycolate derivative of thiol auxiliary 1 is readily prepared (3 steps, 80% overall yield) and has been shown to give excellent anti:syn selectivity (>97:3) and high facial selectivity (88:12 to 97:3) in g
Intramolecular Diels-Alder reactions of tethered homo- and heterotrienes. Synthesis of substituted cyclohexenes and six-membered heterocycles
Craig, Donald,Gordon, Richard S.
, p. 8337 - 8340 (2007/10/03)
Intramolecular Diels-Alder reactions of a number of diester-tethered trienes are reported. All-carbon trienes 5, 7 and 13 show little or no selectivity for trans-fused products. Heterotrienes 21 and 25 exhibit good to excellent cis-selectivity, with low to good selectivity for one of the two cis-fused isomers.
