1398940-13-0

Basic information

• Product Name: N-(4-azido-2-methoxyethoxyphenyl)aza-[18]crown-6 ether
• Synonyms: N-(4-azido-2-methoxyethoxyphenyl)aza-[18]crown-6 ether
• CAS NO: 1398940-13-0
• Molecular Weight: 454.524
• Mol File: 1398940-13-0.mol

Chemical Properties

• CAS DataBase Reference: N-(4-azido-2-methoxyethoxyphenyl)aza-[18]crown-6 ether(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-azido-2-methoxyethoxyphenyl)aza-[18]crown-6 ether(1398940-13-0)
• EPA Substance Registry System: N-(4-azido-2-methoxyethoxyphenyl)aza-[18]crown-6 ether(1398940-13-0)

Safety Data

• Hazardous Substances Data: 1398940-13-0(Hazardous Substances Data)

Upstream product

• 72806-66-7 2-(2-methoxyethoxy)phenylamine 
• 1398940-15-2 2,2'-((2-(2-methoxyethoxy)phenyl)azanediyl)diethanol 
• 1398940-16-3 N-(2-methoxyethoxyphenyl)aza-[18]crown-6 ether 
• 1398940-17-4 N-(4-nitro-2-methoxyethoxyphenyl)aza-[18]crown-6 ether 
• 1398940-18-5 N-(4-amino-2-methoxyethoxyphenyl)aza-[18]crown-6 ether 

Downstream Products

• 1398940-03-8 7-(diethylamino)-3-{1-[3-(2-methoxyethoxy)-4-(1,4,7,10,13-pentaoxa-16-azacyclooctadecan-16-yl)phenyl]-1H-1,2,3-triazol-4-yl}-2H-chromen-2-one 
• 1398940-02-7 16-(4-(4-(anthracen-9-yl)-1H-1,2,3-triazol-1-yl)2-(2-methoxyethoxy)phenyl)-1,4,7,10,13-pentaoxa-16-azacyclooctadecane 

Relevant articles and documents

A highly K+-selective phenylaza-[18]crown-6-lariat-ether-based fluoroionophore and its application in the sensing of K+ ions with an optical sensor film and in cells

Herein, we report the synthesis of two phenylaza-[18]crown-6 lariat ethers with a coumarin fluorophore (1 and 2) and we reveal that compound 1 is an excellent probe for K+ ions under simulated physiological conditions. The presence of a 2-methoxyethoxy lariat group at the ortho position of the anilino moiety is crucial to the substantially increased stability of compounds 1 and 2 over their lariat-free phenylaza-[18]crown-6 ether analogues. Probe 1 shows a high K+/Na+ selectivity and a 2.5-fold fluorescence enhancement was observed in the presence of 100mM K+ ions. A fluorescent membrane sensor, which was prepared by incorporating probe 1 into a hydrogel, showed a fully reversible response, a response time of 150s, and a signal change of 7.8 % per 1mM K+ within the range 1-10mM K+. The membrane was easily fabricated (only a single sensing layer on a solid polyester support), yet no leaching was observed. Moreover, compound 1 rapidly permeated into cells, was cytocompatible, and was suitable for the fluorescent imaging of K+ ions on both the extracellular and intracellular levels. Copyright

Π (PI)-CONJUGATED FLUOROIONOPHORES AND METHOD FOR DETERMINING AN ALKALI ION

The present invention relates to π-conjugated fluoroionophores, methods for their preparation, and their use and a method for determining an alkali ion. Fluoroionophoric compounds of the general formula I are described Ionophore – π-Linker - Fluorophore (