1399147-80-8Relevant academic research and scientific papers
Catalytic enantioselective tert-aminocyclization by asymmetric binary acid catalysis (ABC): Stereospecific 1,5-hydrogen transfer
Chen, Liujuan,Zhang, Long,Lv, Jian,Cheng, Jin-Pei,Luo, Sanzhong
, p. 8891 - 8895 (2012)
Selective H transfer by ABC: A new asymmetric binary acid catalyst was developed to promote 1,5-H transfer specifically and stereoselectively in tert-aminocyclization reactions with excellent activity, high enantioselectivity, and broad substrate scope. The H atom (in red) was proven to transfer through a stereospecific suprafacial pathway (see scheme).
