139965-03-0Relevant academic research and scientific papers
Synthesis of Optically Pure Fluoro- and gem-Chlorofluoro-cyclohexane Derivatives by Intramolecular Trapping of Dihaloalkyl Radicals.
Arnone, Alberto,Bravo, Pierfrancesco,Cavicchio, Giancarlo,Frigerio, Massimo,Viani, Fiorenza
, p. 9 - 12 (1992)
gem-Chlorofluorocyclohexanols 8 bearing a methyl and a p-tolylsulphinyl substituent have been obtained in a optically pure form by radical cyclization of corresponding halo-alkenes 4.Reductive dechlorination of both (6R)- and (6S)-8 gave fluoroderivative
On the Synthesis of Optically Pure Monofluoro cyclohexanol Derivatives by the Fluorinated Sulfoxide Chiron Route
Arnone, Alberto,Bravo, Pierfrancesco,Frigerio, Massimo,Viani, Fiorenza,Cavicchio, Giancarlo,Crucianelli, Marcello
, p. 12361 - 12374 (2007/10/02)
Monofluorocyclohexanols 1 are obtained in optically pure form through radical cyclization of gem-chlorofluoroheptenols 2 which derive from the condensation of α-lithium derivative of sulfoxide of 3 on racemic ethyl chlorofluoroacetate 4, and hydride-promo
Synthesis of Enantiomerically Pure Fluoro- and gem-Chlorofluorocyclohexane Derivatives
Arnone, Alberto,Bravo, Pierfrancesco,Frigerio, Massimo,Viani, Fiorenza,Cavicchio, Giancarlo,Crucianelli, Marcello
, p. 6448 - 6455 (2007/10/02)
gem-Chlorofluorocyclohexanols 10 are prepared in good yields by radical-promoted cyclization from the corresponding ω-dichlorofluoroheptenols 4.Fluorocyclohexanols 11 are obtained either from 10 or in a single step from open-chain alcohols 4.The stereoche
