140-03-4Relevant articles and documents
Boc2O mediated macrolactonisation: Syntheses of R-(+)-ricinoleic acid lactone and (±)-12-OH-stearic acid lactone
Nagarajan
, p. 2467 - 2475 (1999)
An efficient chemoenzymatic synthesis of R-(+)-ricinoleic acid lactone and (±)-12-OH-stearic acid lactone using Boc2O mediated macrolactonisation is reported.
Catalytic cyclopropanation of ricinolic acid derivatives with diazomethane
Davletbakova,Maidanova,Baibulatova,Dokichev,Tomilov,Yunusov,Nefedov
, p. 608 - 611 (2001)
The reaction of ricinolic acid methyl ester with diazomethane in the presence of Co(BF4)2·6H2O results in selective methylation of the hydroxy group. Methyl (2Z, 12R)-12-acetoxy-9-octadecenoate reacts with diazomethane in the presence of Pd(acac)2, leading to formation of a mixture of cis-cyclopropanated (9S, 10S, 12/R)- and (9R, 10R, 12R)-diastereoisomers at a ratio of 3:2 (overall yield 73%). Under similar conditions methyl (9Z)-12-oxo-9-octadecenoate gives rise to optically inactive methyl cis-8-[2-(2-oxooctyl)-cyclopropyl]octanoate.
A process for the preparation of acetyl-ricinoleic acid methyl ester
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Paragraph 0064; 0065, (2016/11/24)
The invention provides a preparation method of methyl acetylricinolate, the preparation method comprises the following steps: step a, using ionic liquid catalyst (Hmim) HSO4 for methyl esterification of castor oil to obtain methyl ricinoleate; and step b: using the ionic liquid catalyst (Hmim) HSO4 for acetylization of the methyl ricinoleate to obtain the methyl acetylricinolate. According to the preparation method, the (Hmim) HSO4 ionic liquid catalyst is used for methyl esterification and acetylation of the castor oil to obtain the methyl acetylricinolate, and the method has the advantages of simple production process, low cost and high product yield, and is conducive to the realization of the industrialized mass production of the methyl acetylricinolate.