1400589-53-8 Usage
Chemical class
Carboxylic acid esters
Derivative
Morpholinecarboxylate
Attached group
7-chloropyrido[3,4-b]pyrazin-5-yl
Amino group attachment
Morpholine ring
Synthesis
Reacting 2-amino-7-chloro-pyrido[3,4-b]pyrazine-5-carbonitrile with (R)-N-Boc-2-hydroxy ethyl morpholine-4-carboxylate
Application
Pharmaceutical and medicinal chemistry
Potential use
Therapeutic properties
Additional use
Research tool in chemical and biological studies
Unique feature
Complex structure and properties
Check Digit Verification of cas no
The CAS Registry Mumber 1400589-53-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,0,5,8 and 9 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1400589-53:
(9*1)+(8*4)+(7*0)+(6*0)+(5*5)+(4*8)+(3*9)+(2*5)+(1*3)=138
138 % 10 = 8
So 1400589-53-8 is a valid CAS Registry Number.
1400589-53-8Relevant articles and documents
PYRIDO[3,4-B]PYRAZINE DERIVATIVES AS SYK INHIBITORS
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Paragraph 0621; 0622; 0623, (2014/02/15)
A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, and autoimmune conditions.
