1400633-92-2

Upstream product

• 71-30-7 Cytosine 
• 1765-93-1 4-fluoroboronic acid 

Downstream Products

• 1400633-94-4 2-chloromethyl-6-(4-fluorophenyl)-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-93-3 4-amino-1-(4-fluorophenyl)-5-iodo-1H-pyrimidin-2-one 
• 1400634-03-8 3-bromo-2-chloromethyl-6-(4-fluorophenyl)-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-48-8 6-(4-fluorophenyl)-2-phenoxymethyl-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-74-0 3-chloro-6-(4-fluorophenyl)-2-phenoxymethyl-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-76-2 6-(4-fluorophenyl)-2-phenoxymethyl-7,8-dihydro-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-86-4 6-(4-fluorophenyl)-3-iodo-2-phenoxymethyl-7,8-dihydro-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-87-5 3-chloro-6-(4-fluorophenyl)-2-phenoxymethyl-7,8-dihydro-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-88-6 3-bromo-6-(4-fluorophenyl)-2-phenoxymethyl-7,8-dihydro-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-51-3 6-(4-fluoro-phenyl)-2-phenoxymethyl-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-59-1 2-(4-fluorophenoxymethyl)-6-(4-fluorophenyl)-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-57-9 6-(4-fluorophenyl)-2-m-tolyloxymethyl-6H-imidazo[1,2-c]pyrimidin-5-one 
• 1400633-63-7 C₁₈H₁₃FN₄O₂ 
• 1400633-64-8 C₁₈H₁₃FN₄O₂ 

Relevant academic research and scientific papers

SUBSTITUTED IMIDAZOPYRIMIDIN-5(6H)-ONES AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS

In one aspect, the invention relates to imidazopyrimidin-5(6H)-one analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

SUBSTITUTED IMADAZAPYRINIDIN-5(6H)-ONES AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS

In one aspect, the invention relates to imidazopyrimidin-5(6H)-one analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.