1400634-52-7

Upstream product

• 105116-40-3 3(S),2(R)-N-[(1,1-dimethylethoxy)carbonyl]-3-amino-2-hydroxy-4-phenylbutyronitrile 
• 72155-45-4 Boc-L-phenylalaninal 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 143238-35-1 C₂₁H₃₈N₂O₃Si 
• 100-52-7 benzaldehyde 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 

Downstream Products

• 1400634-54-9 [(1S,2S)-3-(acetyl(benzyl)amino)-1-benzyl-2-hydroxypropyl]carbamic acid benzyl ester 
• 1400634-53-8 [(1S,2S)-3-(acetyl(benzyl)amino)-1-benzyl-2-(tert-butyl(dimethyl)silanyloxy)propyl]carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Nonpeptidic lysosomal modulators derived from Z-Phe-Ala-diazomethylketone for treating protein accumulation diseases

Lysosomes are involved in protein turnover and removing misfolded species, and their enzymes have the potential to offset the defect in proteolytic clearance that contributes to the age-related dementia Alzheimer's disease (AD). The weak cathepsin B and L