105116-40-3Relevant academic research and scientific papers
Nonpeptidic lysosomal modulators derived from Z-Phe-Ala-diazomethylketone for treating protein accumulation diseases
Viswanathan, Kishore,Hoover, Dennis J.,Hwang, Jeannie,Wisniewski, Meagan L.,Ikonne, Uzoma S.,Bahr, Ben A.,Wright, Dennis L.
, p. 920 - 924 (2013/01/15)
Lysosomes are involved in protein turnover and removing misfolded species, and their enzymes have the potential to offset the defect in proteolytic clearance that contributes to the age-related dementia Alzheimer's disease (AD). The weak cathepsin B and L
Unique Stereocontrol in Europium (III)-Catalyzed Cyanosilylation of chiral α-Alkoxy and α-Amino Aldehydes
Gu, Jin-Hua,Okamoto, Mikako,Terada, Masahiro,Mikami, Koichi,Nakai, Takeshi
, p. 1169 - 1172 (2007/10/02)
The Eu(III)-catalyzed cyanosilylations of chiral α-alkoxy and α-amino aldehydes are shown to exhibit syn diastereofacial selection, the degree increasing with an increase in steric bulk of the alkyl chain in the aldehydes.The mechanism of this catalytic p
