1400889-02-2Relevant academic research and scientific papers
A catalyst-free, three-component decarboxylative coupling of amino acids with aldehydes and H-dialkylphosphites for the synthesis of α- aminophosphonates
Kaboudin, Babak,Karami, Leila,Kato, Jun-Ya,Aoyama, Hiroshi,Yokomatsu, Tsutomu
supporting information, p. 4872 - 4875 (2013/09/02)
A simple, efficient, and new method is developed for the synthesis of α-aminophosphonates via a three-component, catalyst-free decarboxylative coupling of amino acids with aldehydes and H-dialkyl phosphite. Treatment of amino acids with aldehydes and diethyl phosphite in the absence of catalyst, base, and ligand give α-aminophosphonates in moderate to good yields. This method is simple, rapid, and high-yielding.
Cerium(IV) oxide as a neutral catalyst for aldehyde-induced decarboxylative coupling of l-proline with triethyl phosphite and nitromethane
Firouzabadi, Habib,Iranpoor, Nasser,Ghaderi, Arash,Ghavami, Maryam
, p. 5515 - 5518 (2012/11/07)
The application of cerium(IV) oxide (CeO2) as a neutral and heterogeneous catalyst for aldehyde-induced decarboxylative coupling of l-proline with triethyl phosphite and nitromethane is described. In addition, a [3+2] cycloaddition reaction of the in situ generated 1,3-dipolar intermediate with benzaldehyde in the absence of a nucleophile is also reported. 2012 Elsevier Ltd. All rights reserved.
