14009-70-2

Basic information

• Product Name: 18-Methyl Mestranol
• Synonyms: 18-Methyl Mestranol;Levonorgestrel EP impurity V
• CAS NO: 14009-70-2
• Molecular Formula: C22H28O2
• Molecular Weight: 324.45652
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
• Mol File: 14009-70-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 455°Cat760mmHg
• Flash Point: 195.1°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 4.54E-09mmHg at 25°C
• Refractive Index: 1.585
• Storage Temp.: -20°C
• Solubility: Chloroform (Slightly), Methanol (Slightly, Sonicated)
• CAS DataBase Reference: 18-Methyl Mestranol(CAS DataBase Reference)
• NIST Chemistry Reference: 18-Methyl Mestranol(14009-70-2)
• EPA Substance Registry System: 18-Methyl Mestranol(14009-70-2)

Safety Data

• Hazardous Substances Data: 14009-70-2(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 14009-70-2 differently. You can refer to the following data:
1. Mestranol
2. Mestranol (M258755) derivative. It is used as contraceptive.

InChI:InChI=1/C22H28O2/c1-4-21-12-10-18-17-9-7-16(24-3)14-15(17)6-8-19(18)20(21)11-13-22(21,23)5-2/h2,7,9,14,18-20,23H,4,6,8,10-13H2,1,3H3/t18-,19-,20+,21?,22?/m1/s1

Upstream product

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Downstream Products

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Relevant articles and documents

Preparation method of levonorgestrel pharmacopoeia impurity V

The invention belongs to the technical field of pharmacy, and particularly relates to a preparation method of a levonorgestrel pharmacopoeia impurity V. The preparation method comprises the steps of by taking a compound 1 as an initial raw material, carrying out aromatization reaction, methylation reaction and ethynylation reaction to prepare the levonorgestrel pharmacopoeia impurity V; the aromatization method comprises the steps of dissolving the compound 1 with an organic solvent, adding lithium bromide, controlling the temperature to be -5 to 5 DEG C, then adding copper bromide at the temperature, heating to room temperature, reacting and treating to obtain a compound 2. The product obtained by the method is high in purity and yield, avoids generation of impurities, and provides a qualified reference substance for quality control of levonorgestrel.