1401219-43-9

Basic information

• Product Name: N-(3-(pyridin-4-yl)-1-(p-tolyl)-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
• CAS NO: 1401219-43-9
• Molecular Weight: 395.423
• Mol File: 1401219-43-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3-(pyridin-4-yl)-1-(p-tolyl)-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-(pyridin-4-yl)-1-(p-tolyl)-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(1401219-43-9)
• EPA Substance Registry System: N-(3-(pyridin-4-yl)-1-(p-tolyl)-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide(1401219-43-9)

Safety Data

• Hazardous Substances Data: 1401219-43-9(Hazardous Substances Data)

Upstream product

• 25940-35-6 pyrazolo[1,5-a] pyrimidine-3-carboxylic acid 
• 937602-40-9 pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride 
• 23821-37-6 3-oxo-3-(pyridin-4-yl)propanenitrile 
• 539-44-6 N-4-methylphenylhydrazine 

Relevant articles and documents

Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation

IRAK4 is a critical upstream kinase in the IL-1R/TLR signaling pathway. Inhibition of IRAK4 is hypothesized to be beneficial in the treatment of autoimmune related disorders. A screening campaign identified a pyrazole class of IRAK4 inhibitors that were d