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N-(3-(pyridin-4-yl)-1-(p-tolyl)-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1401219-43-9

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1401219-43-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1401219-43-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,1,2,1 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1401219-43:
(9*1)+(8*4)+(7*0)+(6*1)+(5*2)+(4*1)+(3*9)+(2*4)+(1*3)=99
99 % 10 = 9
So 1401219-43-9 is a valid CAS Registry Number.

1401219-43-9Downstream Products

1401219-43-9Relevant academic research and scientific papers

Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation

McElroy, William T.,Tan, Zheng,Ho, Ginny,Paliwal, Sunil,Li, Guoqing,Seganish, W. Michael,Tulshian, Deen,Tata, James,Fischmann, Thierry O.,Sondey, Christopher,Bian, Hong,Bober, Loretta,Jackson, James,Garlisi, Charles G.,Devito, Kristine,Fossetta, James,Lundell, Daniel,Niu, Xiaoda

, p. 677 - 682 (2015/06/30)

IRAK4 is a critical upstream kinase in the IL-1R/TLR signaling pathway. Inhibition of IRAK4 is hypothesized to be beneficial in the treatment of autoimmune related disorders. A screening campaign identified a pyrazole class of IRAK4 inhibitors that were d

AMIDOPYRAZOLE INHIBITORS OF INTERLEUKIN RECEPTOR-ASSOCIATED KINASES

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Page/Page column 153, (2012/10/08)

This invention relates to amidopyrazole compounds that are inhibitors of Interleukin receptor-associated kinases, in particular IRAK-4, and are useful in the treatment of cellular proliferative diseases, for example, cancer, hyperplasia, restenosis, cardiac hypertrophy, immune disorders and inflammation.

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