1401404-46-3

Upstream product

• 32566-01-1 2-(2-aminophenyl)-1H-indole 
• 5720-05-8 4-methylphenylboronic acid 
• 551-93-9 2-aminoacetophenone 
• 40754-13-0 2-(1-(2-phenylhydrazineylidene)ethyl)aniline 
• 88207-45-8 2-(2'-bromophenyl)-1H-indole 
• 104-87-0 4-methyl-benzaldehyde 
• 131298-21-0 2-[(2-aminophenyl)ethynyl]phenylamine 

Relevant academic research and scientific papers

Selective C?H or N?H Imidoylative Annulation of 2-(2-Isocyanophenyl)-1H-indoles Leading to Diverse Indole-fused Scaffolds

2-(2-Isocyanophenyl)-1H-indoles, a class of functionalized isocyanides containing both aromatic C?H and indolo N?H functionalities, are first applied in selective imidoylative annulation reactions. Scaffolds of 6-aryl 11H-indolo[3,2-c]quinoline and 6-aryl

Selective CH or NH Imidoylative Annulation of 2-(2-Isocyanophenyl)-1H-indoles Leading to Diverse Indole-fused Scaffolds

2-(2-Isocyanophenyl)-1H-indoles, a class of functionalized isocyanides containing both aromatic CH and indolo NH functionalities, are first applied in selective imidoylative annulation reactions. Scaffolds of 6-aryl 11H-indolo[3,2-c]quinoline and 6-aryl i

A 11H - indolo [3, 2 - c] quinoline synthetic method of compound

The invention discloses a synthesis method of 11H-indolo [3,2-c] quinoline compounds, belonging to the technical field of synthesis of indolo quinoline compounds. The technical scheme of the invention is mainly characterized by taking 2-(2-bromo-aryl)-1H-indolo, ammonia water and aldehyde compounds as raw materials, taking dimethyl sulfoxide or N,N-dimethyl formamide as a solvent, taking transition metal salt as a catalyst, taking potassium carbonate as alkali, and taking L-proline as a ligand to carry out one-pot, two-step and three-component tandem reaction to synthesize 11H-indolo [3,2-c] quinoline compounds with multiple substitute modes. The synthesis method disclosed by the invention has the advantages that starting materials are simple and easy to prepare, and substrates are wide in range of application, high in regioselectivity and simple in operation.

Regioselective Synthesis of Indolo[1,2-c]quinazolines and 11H-Indolo[3,2-c]quinolines via Copper-Catalyzed Cascade Reactions of 2-(2-Bromoaryl)-1H-indoles with Aldehydes and Aqueous Ammonia

Highly selective and convenient synthesis of indolo[1,2-c]quinazolines and 11H-indolo[3,2-c]quinolines through copper-catalyzed one-pot cascade reactions of 2-(2-bromoaryl)-1H-indoles with aldehydes and aqueous ammonia has been achieved. Notably, the regioselectivity was easily controlled by tuning the reaction conditions. Compared with literature methods, the present protocol features easily controlled selectivity, readily available starting materials, good functional group tolerance, and simple operation procedures.

An alternative one-pot gold-catalyzed approach to the assembly of 11H-indolo[3,2-c]quinolines

A new one-pot approach was developed to construct the 11H-indolo[3,2-c] quinoline scaffold through a gold-catalysed reaction of 2-[(2-aminophenyl) ethynyl]phenylamine derivatives with aldehydes. The broad scope and the high regioselectivity of this new pr