1401512-99-9Relevant academic research and scientific papers
Green synthesis of some novel chalcone and isoxazole substituted 9-anilinoacridine derivatives and evaluation of their antimicrobial and larvicidal activities
Kalirajan,Mohammed Rafick,Sankar,Gowramma
, p. 583 - 590 (2019/05/21)
Synthesis of some novel 9-anilinoacridine derivatives 3a-j and 4a-j from 9-cloroacridine under MW irradiation have been reported. The structures of the synthesized compounds have been confirmed by physical and analytical data. The synthesized compounds have been screened for their in vitro anti-microbial activities against Staphylococcus aureus, Bacillus megaterium, Escherichia coli, Klebsiella pneumoniae, Candida albicans and Aspergillus Niger. Their larvicidal activity against Culex quinquefasciatus and Anopheles stephensi have also been screened by larval bioassay method. Many of the compounds have significant antimicrobial and larvicidal activities.
Synthesis of some novel pyrazole-substituted 9-anilinoacridine derivatives and evaluation for their antioxidant and cytotoxic activities
Kalirajan,Muralidharan,Jubie,Gowramma,Gomathy,Sankar,Elango
, p. 748 - 754 (2012/10/29)
This article focuses on the synthesis of new series of pyrazole-substituted 9-anilinoacridine derivatives 5a-m and 6a-l. The compounds were confirmed by physical and analytical data. The synthesized compounds when screened for in vitro antioxidant activity showed promising activity for many compounds. The selected compounds were screened for cytotoxic activity showed promising inhibition of HEp-2 cell line for the compounds 6c, 6e, and 6f.
