1401520-03-3Relevant articles and documents
N-heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes: Asymmetric synthesis of 5-carbon-synthon δ-nitroesters
Maji, Biswajit,Ji, Li,Wang, Siming,Vedachalam, Seenuvasan,Ganguly, Rakesh,Liu, Xue-Wei
supporting information; experimental part, p. 8276 - 8280 (2012/09/07)
Synthesizing synthons: The highly enantioselective title reaction is described. It employs catalytic amounts of N-heterocyclic carbene precursors and transforms a broad range of nitroalkenes, such as nitrodienes, nitroenynes, and nitrostyrenes, through reaction with a broad range of enals, into δ-nitroesters via homoenolate intermediates (see scheme). Copyright