14016-29-6

Basic information

• Product Name: averufin
• Synonyms: averufin;3,4,5,6-Tetrahydro-7,9,11-trihydroxy-2-methyl-2,6-epoxy-2H-anthra[2,3-b]oxocin-8,13-dione;(1'S,5'S)-averufin
• CAS NO: 14016-29-6
• Molecular Formula: C₂₀H₁₆O₇
• Molecular Weight: 0
• Mol File: 14016-29-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 602.9°Cat760mmHg
• Flash Point: 220.8°C
• Appearance: /
• Density: 1.585g/cm³
• Vapor Pressure: 3.94E-15mmHg at 25°C
• Refractive Index: 1.718
• CAS DataBase Reference: averufin(CAS DataBase Reference)
• NIST Chemistry Reference: averufin(14016-29-6)
• EPA Substance Registry System: averufin(14016-29-6)

Safety Data

• Hazardous Substances Data: 14016-29-6(Hazardous Substances Data)

Usage

Definition

ChEBI: An organic heteropentacyclic compound that is 3,4,5,6-tetrahydro-2H-2,6-epoxyanthra[2,3-b]oxocine-8,13-dione substituted at position 2 by a methyl group and at positions 7, 9 and 11 by hydroxy groups (the S, stereo>S-diastereomer)

InChI:InChI=1/C20H16O7/c1-20-4-2-3-12(26-20)16-13(27-20)7-10-15(19(16)25)18(24)14-9(17(10)23)5-8(21)6-11(14)22/h5-7,12,21-22,25H,2-4H2,1H3

Upstream product

• 67-56-1 methanol 

Downstream Products

• 111975-78-1 1'-hydroxyversicolorone 
• 74810-25-6 avefurin triacetate 

Relevant articles and documents

Quinofuracins A-E, produced by the fungus staphylotrichum boninense PF1444, show p53-dependent growth suppression

Quinofuracins A-E, novel anthraquinone derivatives containing β-d-galactofuranose that were isolated from the fungus Staphylotrichum boninense PF1444, induced p53-dependent cell death in human tumor cells. The structures of quinofuracins A-E, including absolute configurations, were elucidated by extensive spectroscopic analysis and chemical transformation studies. Quinofuracins were classified into three groups according to the aglycone moieties. 5'-Oxoaverantin was present in quinofuracins A-C, whereas averantin and versicolorin B were identified in quinofuracins D and E, respectively. These quinofuracins induced p53-dependent growth suppression in human glioblastoma LNZTA3 cells.