1401693-85-3Relevant academic research and scientific papers
Iodine-Catalyzed Ring Opening of 1,1-Diacylcyclopropanes for Synthesis of Fully Substituted Pyrazole Derivatives
Bao, Yishu,Chen, Ming,Ding, Ziyu,Yang, Fulai,Yang, Xiuqin,Zhou, Qingfa,Zhu, Jin
supporting information, (2020/07/04)
An iodine-catalyzed [3+2] cycloaddition/ring opening reaction of 1,1-diacylcyclopropanes with sulfonyl hydrazides has been reported. In the presence of 20 mol-% iodine, a range of structurally diverse fully substituted pyrazoles with a hydroxy functional group are obtained in moderate to excellent yields with extremely high regioselectivity.
