1402228-07-2Relevant academic research and scientific papers
Copper-mediated and copper-catalyzed cross-coupling of indoles and 1,3-azoles: Double C-H activation
Nishino, Mayuko,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
supporting information; experimental part, p. 6993 - 6997 (2012/10/07)
A new bronze age: The described copper-mediated cross-coupling with double C-H activation can provide a convergent access to indole-containing biheteroaryls that are of high interest in pharmaceutical and medicinal chemistry. In this strategy an easily attachable and detachable 2-pyrimidyl directing group is used. Moreover, a variant that is catalytic in copper is achieved by using atmospheric oxygen as an ideal co-oxidant (see scheme). Copyright
