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Usage

Uses

Used in Pharmaceutical Industry:
Trilobacin is used as a cytotoxic agent for its ability to inhibit the growth and proliferation of cancer cells. It has shown potential in targeting various types of cancer cells, making it a valuable compound for further research and development in the field of oncology.
Used in Cancer Research:
Trilobacin is utilized as a research tool for studying the mechanisms of cytotoxicity and cell death in cancer cells. Its use in cancer research can contribute to the understanding of cancer biology and the development of novel therapeutic strategies.
Used in Drug Development:
Trilobacin serves as a starting point for the development of new anticancer drugs. Its cytotoxic properties can be further optimized and modified to improve its efficacy and selectivity towards cancer cells, potentially leading to the creation of more effective cancer treatments.

InChI:InChI=1/C37H66O7/c1-3-4-5-6-7-11-14-17-20-31(39)33-22-24-35(43-33)36-25-23-34(44-36)32(40)21-18-15-12-9-8-10-13-16-19-30(38)27-29-26-28(2)42-37(29)41/h26,28,30-36,38-40H,3-25,27H2,1-2H3

Upstream product

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• 303053-12-5 (4R,5R)-1-iodo-4,5-isopropylidenedioxypentadecane 
• 202067-10-5 (4R,5R)-4,5-isopropylidenedioxypentadecanol 
• 303053-11-4 (4R,5R)-Pentadecane-1,4,5-triol 
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Relevant academic research and scientific papers

Asymmetric total synthesis of trilobacin via organoselenium-mediated oxonium ion formation/SiO2-Promoted fragmentation

An asymmetric total synthesis of trilobacin (1), an annonaceous acetogenin with potent anticancer activities, was accomplished wherein the construction of its erythro-bis(2,2′)-tetrahydrofuran core 2 featured a novel organoselenium-mediated oxonium ion formation/SiO2-promoted fragmentation of α,α′-cis-oxocene 3.