140226-15-9

Upstream product

• 59676-20-9 9-(2,5-dideoxy-β-D-glycero-pent-4-enofuranosyl)adenine 
• 111570-92-4 N⁶-benzoyl-3'-O-(tert-butyldiphenylsilyl)-2'-deoxyadenosine 
• 958-09-8 2'-deoxy-D-adenosine 
• 140226-12-6 9-<3-O-(tert-butyldimethylsilyl)-2,5-dideoxy-β-D-glycero-pent-4-enofuranosyl>adenine 
• 140226-18-2 2',5'-dideoxy-5'-iodoadenosine 
• 67-56-1 methanol 
• 201420-68-0 N-[9-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-5-phenylselanyl-tetrahydro-furan-2-yl)-9H-purin-6-yl]-benzamide 
• 140226-13-7 3'-O-(tert-butyldimethylsilyl)-2'-deoxy-4'-methoxyadenosine 

Relevant academic research and scientific papers

Straightforward Synthesis of Purine 4′-Alkoxy-2′-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4′-Alkoxyoligodeoxynucleotides as New RNA Mimics

Purine and pyrimidine 4′-alkoxy-2′-deoxynucleosides were efficiently prepared from nucleoside 4′-5′-enol acetates in three steps by N-iodosuccinimide promoted alkoxylation, hydrolysis, and reduction followed by conversion to phosphoramidite monomers for t

Oxidation of 4'-deoxyribonucleoside radicals to 4'-deoxyribonucleoside cations. A model for the function of bleomycin

Selective generation of the 4'-deoxyribonucleoside radical 8 in the presence of Mn(OAc)3 gave acetal 9 in 91% yield. This reaction models the function of the antibiotic bleomycin under diminished O2 concentrations. In the presence of O2 a peroxy radical is formed that leads to completely different products.

Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides

A series of nucleosides were synthesized in which the 4'-hydrogen was substituted with either an azido or a methoxy group. The key steps in the syntheses of the 4'-azido analogues were the stereo- and regioselective addition of iodine azide to a 4'-unsatu