140226-15-9

Basic information

• Product Name: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-2-methoxytetrahydrofuran-3-ol (non-preferred name)
• Synonyms: 2'-Deoxy-4'-methoxyadenosine
• CAS NO: 140226-15-9
• Molecular Formula: C₁₁H₁₅N₅O₄
• Molecular Weight: 281.2679
• Mol File: 140226-15-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 615.6°C at 760 mmHg
• Flash Point: 326.1°C
• Density: 1.78g/cm³
• Vapor Pressure: 5.21E-16mmHg at 25°C
• Refractive Index: 1.767
• CAS DataBase Reference: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-2-methoxytetrahydrofuran-3-ol (non-preferred name)(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-2-methoxytetrahydrofuran-3-ol (non-preferred name)(140226-15-9)
• EPA Substance Registry System: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-2-methoxytetrahydrofuran-3-ol (non-preferred name)(140226-15-9)

Safety Data

• Hazardous Substances Data: 140226-15-9(Hazardous Substances Data)

Upstream product

• 111570-92-4 N⁶-benzoyl-3'-O-(tert-butyldiphenylsilyl)-2'-deoxyadenosine 
• 140226-18-2 2',5'-dideoxy-5'-iodoadenosine 
• 59676-20-9 9-(2,5-dideoxy-β-D-glycero-pent-4-enofuranosyl)adenine 
• 67-56-1 methanol 
• 201420-68-0 N-[9-((2R,4S,5R)-4-Hydroxy-5-hydroxymethyl-5-phenylselanyl-tetrahydro-furan-2-yl)-9H-purin-6-yl]-benzamide 
• 140226-13-7 3'-O-(tert-butyldimethylsilyl)-2'-deoxy-4'-methoxyadenosine 
• 958-09-8 2'-deoxy-D-adenosine 
• 140226-12-6 9-<3-O-(tert-butyldimethylsilyl)-2,5-dideoxy-β-D-glycero-pent-4-enofuranosyl>adenine 

Relevant articles and documents

Straightforward Synthesis of Purine 4′-Alkoxy-2′-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4′-Alkoxyoligodeoxynucleotides as New RNA Mimics

Purine and pyrimidine 4′-alkoxy-2′-deoxynucleosides were efficiently prepared from nucleoside 4′-5′-enol acetates in three steps by N-iodosuccinimide promoted alkoxylation, hydrolysis, and reduction followed by conversion to phosphoramidite monomers for t

Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides

A series of nucleosides were synthesized in which the 4'-hydrogen was substituted with either an azido or a methoxy group. The key steps in the syntheses of the 4'-azido analogues were the stereo- and regioselective addition of iodine azide to a 4'-unsatu