140238-69-3

Upstream product

• 625-28-5 Isovaleronitrile 
• 111-66-0 oct-1-ene 
• 14850-23-8 trans-4-Octene 
• 111-67-1 2-octene 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 

Relevant academic research and scientific papers

Ni-Catalyzed Isomerization-Hydrocyanation Tandem Reactions: Access to Linear Nitriles from Aliphatic Internal Olefins

A highly regioselective nickel-based catalyst system for the isomerization/hydrocyanation of aliphatic internal olefins is described. This benign tandem reaction provides facile access to a wide variety of aliphatic nitriles in good yields with excellent regioselectivities. Thanks to Lewis acid-free conditions, the protocol features board functional groups tolerance, including secondary amine and unprotected alcohol groups.

Process for the Catalytic Reversible Alkene-Nitrile Interconversion

The present invention refers to processes for catalytic reversible alkene-nitrile interconversion through controllable HCN-free transfer hydrocyanation.